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- Healthy kidney function is vital for removing
metabolic waste products from the blood and for maintaining
healthy cholesterol levels. Diabetics are particularly
susceptible to poor kidney health due to high blood
sugar levels. Some researchers have suggested that more
vegetable protein supports better kidney health (1-3).
More specifically, medical studies suggest that soy
protein with its isoflavones may have multiple benefits
for supporting kidney health (4,5),
and is an excellent choice for adding vegetable protein
to one’s diet.
In a randomized clinical trial, Type II diabetics were
instructed to replace their usual diet with a soy-enriched
diet (6). Switching to the soy diet
reduced the amount of protein and nitrogen in the urine
suggesting a favorable effect on kidney function. Also,
soy consumption reduced total cholesterol, LDL cholesterol
and triglycerides. Similar lipid lowering effects also
have been observed in renal transplant patients (7).
People on dialysis, who are prone to protein malnutrition,
may also benefit. Preliminary data University of Kentucky
reveals that dialysis patients, when given soy protein,
experience a decrease in protein malnutrition, suggesting
that soy protein may be beneficial in supporting a better
nutritional status in dialysis patients (8).
If you are interested in soy and kidney health support,
ask your health care professional about adding more
soy to your diet.
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References:
1. Kontessis PA, Bossinakou I, Sarika
L, Iliopoulou E, Papantoniou A, Trevisan R, Roussi D,
Stipsanelli K, Grigorakis S, Souvatzoglou A. Renal,
metabolic, and hormonal responses to proteins of different
origin in normotensive, nonproteinuric type I diabetic
patients. Diabetes Care 1995; 18(9):1233.
2. Soroka N, Silverberg DS, Greemland
M, Birk Y, Blum M, Peer G, Iaina A. Comparison of a
vegetable-based (soya) and an animal-based low-protein
diet in predialysis chronic renal failure patients.
Nephron 1998; 79(2):173-180.
3. Kitazato H, Fujita H, Shimotomai
T, Kagaya E, Narita T, Kakei M, Ito S. Effects of chronic
intake of vegetable protein added to animal or fish
protein on renal hemodynamics. Nephron 2002; 90:31-36.
4. Anderson JW, Smith BM, Washmock CS.
Cardiovascular and renal benefits of dry bean and soybean
intake. American Journal of Clinical Nutrition 1999;
70(Suppl 3):464S-474S.
5. Ranich T, Bhathena SJ, Velasquez
MT. Protective effects of dietary phytoestrogens in
chronic renal disease. Journal of Renal Nutrition 2001;
11(4):183-193.
6. Azadbakht L, Shakerhosseini R, Atabak
S, Jamshidian M, Mehrabi Y, Esmaill-Zadeh A. Beneficiary
effect of dietary soy protein on lowering plasma levels
of lipid and improving kidney function in type II diabetes
with nephropathy. European Journal of Clinical Nutrition
2003; 57(10):1292-1294.
7. Cupisti A, D’Alessandro C,
Ghiadoni L, Morelli E, Panichi V, Barsotti G. Effect
of soy protein diet on serum lipids of renal transplant
patients. Journal of Renal Nutrition 2004; 14(1):31-35.
8. Dietary Intake of a Soy Protein Isolate
Supplement Improves Nutritional Status in Malnourished
Hemodialysis Patients. T. J. Stephenson, et al. Fourth
International Symposium on the Role of Soy in Preventing
and Treating Chronic Disease, Nov. 4-7, 2001. San Diego,
California.
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